Recent advances in culture-based gut microbiome research

Gut microbes affect the physiology of their hosts. Studying diversity and functions is thus utmost importance as it will open new avenues towards discovery biomolecules treatment diseases. microbiome research currently boosted by unification metagenomics, which has dominated field in last two decades, cultivation, experiencing a renaissance. Each these approaches advantages drawbacks that can be overcome if used synergistically. In this brief article, we summarize recent literature own studies on cultivation gut microbes, provide succinct status quo cultured fractions collections isolates, give short opinions challenges next steps to take.